The pioneering artist always lived out loud, even when the world tried to silence and ignore him.
The show, at the city's Seminole Hard Rock Hotel & Casino, will be for an audience of 7,000 fans.
The metal titans will be playing exclusive shows at the city’s Chase Center on 17 and 19 December.
For some 1967’s Summer of Love had its origins at this historic counter-culture event.
The pre-recorded show will be broadcast at drive-ins across North America later this month.
The San Francisco festival will be cancelled this year, amid the coronavirus.
The countdown timer is due to hit zero on Thursday, 10 October at 12 noon (GMT).
Metallica say: “The response to the two S&M2 shows earlier this month at San Francisco’s new Chase Center has been nothing short of mind-boggling."
Quicksilver swiftly built up a following as part of the San Francisco acid rock scene with the likes of Jefferson Airplane and The Grateful Dead during the late 1960s.
The recordings were captured during the fabled NYC outfit's multiple-night residency at the San Francisco nightspot late in 1969.
The film, which is directed by Adam Dubin, is set to premiere on 20 April at AMC Kabuki 8 in San Francisco.
The special, one-off event is to mark the 20th anniversary of the metal titans' 1999 live LP, 'S&M.'
The seventh annual Metallica night with baseball’s San Francisco Giants will take place on 26 April.
The initiative, through the band’s All Within My Hands Foundation, will see 10 colleges receive $100,000 each.
Legendary rocker and former Montrose mainstay has joined fellow inductees Metallica, Bonnie Raitt and Journey on San Francisco's Bammies Walk Of Fame.