KISS, Iron Maiden and System Of A Down were due to headline Download, while the Isle Of Wight was set to host Lewis Capaldi, The Chemical Brothers and Lionel Richie.
Other big names on the bill include Run The Jewels, Rick Astley and The Stone Roses' Ian Brown.
Other winners on the list include Snow Patrol's Gary Lightbody and Olivia Newton-John.
The iconic UK festival will return once between 11 and 14 June, with the above acts topping the bill across the entire weekend.
The record accompanies a ‘Reworked’ tour starting on 13 November through to 5 December
The 'Reworked' tour touches down in cities including London, Oxford, Dublin, and Belfast.
The new release also includes 'Time Won't Go Slowly' and new versions of ‘Open Your Eyes’ & ‘Chocolate’.
The original recording of the track featured on Snow Patrol’s 2008 album, 'A Hundred Million Suns.'
Singer Gary Lightbody has described the track as “the purest love song” he has ever written.
The new track follows the band's most recent album 'Wildness', their first studio set in seven years, which reached No. 2 in the UK album charts.
Last year's event saw headlining sets from Queen + Adam Lambert, The Killers and Arctic Monkeys.
The headlining acts will be joined by Loyle Carner, Sigrid, Tom Grennan, Primal Scream and Cat Power.
Part One of the series' first season debuted in September, featuring TLC, Moby, Noel Gallagher and Nile Rodgers.
Double-disc editions of 'A Hundred Million Suns', 'Eyes Open' and 'Fallen Empires' are now available, as is a new single disc reissue of 'Final Straw'.
The 21-date trek takes in shows in Austin, Nashville, Boston, New York, Toronto, Los Angeles and more.