The tour will kick off on 23 April in Louisville, KY and will end in Greensboro, NC on 8 May.
"It’s going to feel like a homecoming and we are very excited", The Edge said of the forthcoming dates.
AFI will also join the tour as special guest on all the dates.
Sir Cliff Richard was also confirmed for the high-profile London festival last month.
The 1975 and The National are among the big names already confirmed for the Madrid-based festival next year.
This year's star-studded event also features Noel Gallagher's High Flying Birds, Gary Barlow and The Waterboys.
Emeli Sandé, Tom Jones and Noel Gallagher's High Flying Birds are among the big names confirmed for the 2018 Greenwich Music Time Concerts
Noel Gallagher's High Flying Birds have announced the release of a new album Who Built The Moon, due out in November 2017 on Caroline International