The Stereophonics’ frontman is also releasing a new solo set of the same name featuring an intimate, acoustic spin on his band’s biggest tracks.
Other titles set to premiere at the festival include the new the much-anticipated Phil Lynott documentary, 'Songs For While I'm Away'.
The band said, "It’s time to gear up for three nights of coffee shop takeovers, boat parties, world-famous DJs and of course, a full Streets concert."
Held at the UK city's Sandwell Valley Country Park, the event will take place on July 31 next year.
The single, featuring IDLES, marks the title track off The Streets’ acclaimed new mixtape.
The show, at Earth in Hackney, will launch Mike Skinner's new mixtape, 'None Of Us Are Getting Out Of This Life Alive.'
The new collection is available via all streaming services as well as on standard and gold vinyl LP and cassette via Island Records.
The Charlatans frontman's previous listening parties have delved into lauded albums by The Chemical Brothers, Steven Wilson and The Streets.
The song, featuring Hak Baker, comes off ‘None Of Us Are Getting Out Of This Life Alive’, out 10 July.
Other stars taking part include Ash, Brand New Heavies, Embrace, Gary Numan and Tony Hadley.
The single, feat. Donae'o and Greentea Peng, comes ahead of The Streets’ anticipated new mixtape, ‘None of Us Are Getting Out of This Life Alive’, out 10 July.
The virtual festival will air on a pop-up channel from 24 to 28 June to mark what would have been Glastonbury's 50th anniversary.
The new tune will also feature on Mike Skinner’s incoming mixtape, 'None Of Us Gets Out Of This Life Alive', set for release on 10 July.
The party will be followed at 11pm by the YouTube premiere of The Streets’ documentary, 'The A-Z Of How To Make A Mixtape'.
The new song is also the flip to The Streets' recent single 'Call My Phone Thinking I'm Doing Nothing Better’ featuring Tame Impala.