Jonas Brothers Share New Single ‘I Can’t Lose’
The track is the third single from their album ‘Greetings From Your Hometown,’ out on August 8.

The Jonas Brothers are keeping their hot streak alive with their latest single “I Can’t Lose.” The third single from their forthcoming album Greetings From Your Hometown, “I Can’t Lose” is a stomping and anthemic track about the support of a partner. The band debuted the music video for the track during the 2025 MLB All-Star Game, and the track is the first official anthem for ESPN’s Sunday Night Baseball.
Released with the support of Mastercard for its Stand Up To Cancer campaign, the music video for “I Can’t Lose” is “dedicated to everyone standing up to cancer” and sees the brothers performing the track on a New York City rooftop. Several cancer survivors join them on the roof for the performance, which is intercut with the survivors’ stories of battling the disease.
In addition to Greetings From Your Hometown, the Jonas Brothers are about to embark on a tour to support the album and to celebrate their 20-year career. From August until November, the brother band will play dates across the United States and Canada with support from Marshmello, The All-American Rejects, and Boys Like Girls. Beyond the band’s work, the tour will also spotlight music from both Nick Jonas’ and Joe Jonas’ solo careers, Joe’s work with DNCE, and music from Nick Jonas & the Administration. Tickets for the JONAS20: Greetings From Your Hometown tour are available now.
“I Can’t Lose” comes on the heels of the band’s last single, “No Time To Talk,” which boasts an interpolation of the Bee Gees classic “Stayin’ Alive.” The first single from Greetings From Your Hometown, “Love Me To Heaven,” arrived in March. The album will also include the band’s most recent collaboration with electronic music producer Marshmello, “Slow Motion,” which arrived in January. Greetings From Your Hometown will be the band’s third album since their 2019 reunion, and their seventh overall.