DaBaby, Justin Bieber, Phoebe Bridgers, Billie Eilish, and Dua Lipa are also among the top contenders.
The new clip was directed by the band’s own Jeon Jung-kook.
Released on August 21, the song topped the U.S. Billboard's Hot 100 singles chart three times and remained in the top 10 until the 11th week of its release.
The yuletide edition of the popular lockdown series kicks off the holiday season on November 30.
The K-Pop superstars' new album is set for release through Big Hit Entertainment on November 20.
Performers for the November 22 awards show also include BTS, Megan Thee Stallion, Bad Bunny, and Dua Lipa.
The K-pop superstars were the night's hottest news, earning four awards for Best Song, Best Group, Best Virtual Live and Biggest Fans.
Scheduled for December 6, the event is set to be broadcast virtually to a global audience.
The new game is available exclusively through the Weverse app on November 10.
A socially distanced affair, this year's ceremony was finally happened live on NBC, broadcast from the Dolby Theatre in Los Angeles.
2020 marks the 27th edition of the show, which is set to air globally via MTV on Sunday, November 8.
The K-Pop superstars debut album, titled simply 'The Album' is also set for release on October 2.
Host Jimmy Fallon said, “I’m so excited to have BTS back. We just started the new season and we’re working on a lot of really exciting things."
K-pop supergroup BTS brought their A-game for their debut NPR Tiny Desk Performance, taking on ‘Dynamite,’ ‘Save Me’, and ‘Spring Day.’
The virtual event also featured Alicia Keys Coldplay, Thomas Rhett and more.