Stars set to appear include Garth Brooks, George Strait, and more.
On February 12, 1963, the Texan hitmaker recorded the signature track that became his first No.1 and attracted the attention of The Beatles.
On January 7, 1967, Pride became the first African-American solo singer to perform on the radio show and live institution that was the Grand Ole Opry.
The show will feature interviews with the star and contributions from Darius Rucker, Loretta Lynn, Shania Twain, and more.
Pride's rise from humble origins picking cotton for his father in Mississippi to becoming country's first Black superstar were universally acknowledged.
'Moanin' The Blues,' which entered the country chart on 18 November 1950, became Hank's next No. 1 in the last week of the year.
He will receive the honor during the 54th Annual CMA Awards in Nashville on November 11.
The barrier-breaking star celebrates a quarter-century since his induction.
Nina Simone, the Velvet Underground, Sly Stone, Jimmie Rodgers and others will receive the Recording Academy's Lifetime Achievement Awards for 2017.
'Forever Country,' the all-star single released by 30 CMA Award-winning artists, is off to a spectacular start on sales, streaming and airplay charts.
'Forever Country,' the multi-artist song and accompanying video created to celebrate the upcoming 50th CMA Awards, has made its worldwide radio debut.